Dr.rer.nat. Christian Karsten

Institute for Systemic Inflammation Research (ISEF)
University of Lübeck

E-Mail: christian.karsten(at)uksh.de
Tel.: 0049 451 500 51423

Recent Publications:

1.Kulkarni U, Karsten CM, Kohler T, Hammerschmidt S, Bommert K, Tiburzy B, Meng L, Thieme L, Recke A, Ludwig RJ, Pollok K, Kalies K, Bogen B, Boettcher M,Kamradt T, Hauser AE, Langer C, Huber-Lang M, Finkelman FD, Köhl J, Wong DM, ManzRA. IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration. J Allergy Clin Immunol. 2015 Dec 1. PubMed PMID: 26653800.

2. Karsten CM, Köhl J. A bone to pick with Fc gamma receptors. Ann Transl Med.2015 Sep;3(15):218. PubMed PMID:26488014.

3: Karsten CM, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, Czabanska A, Vollbrandt T, Figge J, Köhl J. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015 Feb 15;194(4):1841-55. PubMed PMID: 25589074.

4: Chen H, Assmann JC, Krenz A, Rahman M, Grimm M, Karsten CM, Köhl J,  Offermanns S, Wettschureck N, Schwaninger M. Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE. J Clin Invest. 2014 May;124(5):2188-92. PubMed PMID: 24691444.

5: Karsten CM, Laumonnier Y, Köhl J. Functional analysis of C5a effector responses in vitro and in vivo. Methods Mol Biol. 2014;1100:291-304. PubMed PMID: 24218268.

6: Bär F, Föh B, Pagel R, Schröder T, Schlichting H, Hirose M, Lemcke S, Klinger A, König P, Karsten CM, Büning J, Lehnert H, Fellermann K, Ibrahim SM, Sina C. Carboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in mice. PLoS One. 2014 Jul 22;9(7):e102347. PubMed PMID: 25051500.

7: Schmudde I, Ströver HA, Vollbrandt T, König P, Karsten CM, Laumonnier Y, Köhl J. C5a receptor signalling in dendritic cells controls the development of maladaptive Th2 and Th17 immunity in experimental allergic asthma. Mucosal Immunol. 2012 Dec 5. PubMed PMID: 23212198.

8: Le Friec G, Sheppard D, Whiteman P, Karsten CM, Shamoun SA, Laing A, Bugeon L, Dallman MJ, Melchionna T, Chillakuri C, Smith RA, Drouet C, Couzi L, Fremeaux-Bacchi V, Köhl J, Waddington SN, McDonnell JM, Baker A, Handford PA, Lea SM, Kemper C. The CD46-Jagged1 interaction is critical for human TH1 immunity. Nat Immunol. 2012 Dec;13(12):1213-21. Epub 2012 Oct 21. PubMed PMID: 23086448.

9: Karsten CM, Köhl J. The immunoglobulin, IgG Fc receptor and complement triangle in autoimmune diseases. Immunobiology. 2012 Nov;217(11):1067-79. PubMed PMID: 22964232.

10: Karsten CM, Pandey MK, Figge J, Kilchenstein R, Taylor PR, Rosas M, McDonald JU, Orr SJ, Berger M, Petzold D, Blanchard V, Winkler A, Hess C, Reid DM, Majoul IV, Strait RT, Harris NL, Köhl G, Wex E, Ludwig R, Zillikens D, Nimmerjahn F, Finkelman FD, Brown GD, Ehlers M, Köhl J. Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcgammaRIIB and dectin-1. Nat Med.2012 Sep;18(9):1401-6. PubMed PMID: 22922409.

See all publications on PubMed