Claire Chougnet, PhD, Associate Professor

Division of Cellular and Molecular Immunology
Cincinnati Children’s Hospital Medical Center

E-Mail: claire.chougnet(at)cchmc.org
Tel.: 001 513 636 8847

Recent publications:

1.  Moreno-Fernandez ME, Aliberti J, Groeneweg S, Köhl J, Chougnet CA. A Novel Role for the Receptor of the Complement Cleavage Fragment C5a, C5aR1, inCCR5-Mediated Entry of HIV into Macrophages. AIDS Res Hum Retroviruses. 2015 Dec 15. PMID: 26537334

2. Sweeney EL, Kallapur SG, Gisslen T, Lambers DS, Chougnet CA, Stephenson SA,Jobe AH, Knox CL. Placental Infection With Ureaplasma species Is Associated With Histologic Chorioamnionitis and Adverse Outcomes in Moderately Preterm and Late-Preterm Infants. J Infect Dis. 2015 Dec 15. PubMed PMID: 26671889.

3. Chougnet CA, Thacker RI, Shehata HM, Hennies CM, Lehn MA, Lages CS, JanssenEM. Loss of Phagocytic and Antigen Cross-Presenting Capacity in Aging DendriticCells Is Associated with Mitochondrial Dysfunction. J Immunol. 2015 Sep15;195(6):2624-32. PubMed PMID:26246142. 

4. Rueda CM, Moreno-Fernandez ME, Jackson CM, Kallapur SG, Jobe AH, Chougnet CA. Neonatal regulatory T cells have reduced capacity to suppress dendritic cell function. Eur J Immunol. 2015 Sep;45(9):2582-92. PubMed PMID: 26046326.

5. Nikiforou M, Vanderlocht J, Chougnet CA, Jellema RK, Ophelders DR, Joosten M, Kloosterboer N, Senden-Gijsbers BL, Germeraad WT, Kramer BW, Wolfs TG. Prophylactic Interleukin-2 Treatment Prevents Fetal Gut Inflammation and Injuryin an Ovine Model of Chorioamnionitis. Inflamm Bowel Dis. 2015 Sep;21(9):2026-38. PubMed PMID: 26002542.

6. Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA. IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age. J Immunol. 2015 Aug 1;195(3):944-52. doi: 10.4049/jimmunol.1500443. Epub 2015 Jun24. PubMed PMID: 26109645.

7. Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y, Liu Z, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, MoJ, Filipovich AH, Bleesing JJ, Mustillo P, Stephens M, Rueda CM, Chougnet CA, Hoebe K, McElwee J, Hughes JD, Karakoc-Aydiner E, Matthews HF, Price S, Su HC,Rao VK, Lenardo MJ, Jordan MB. AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy. Science. 2015 Jul 24;349(6246):436-40. PubMed PMID:26206937.

8: Shehata HM, Hoebe K, Chougnet CA. The aged nonhematopoietic environment impairs natural killer cell maturation and function. Aging Cell. 2015 Apr;14(2):191-9. PubMed PMID: 25677698.

9: Presicce P, Senthamaraikannan P, Alvarez M, Rueda CM, Cappelletti M, Miller LA, Jobe AH, Chougnet CA, Kallapur SG. Neutrophil recruitment and activation in decidua with intra-amniotic IL-1beta in the preterm rhesus macaque. Biol Reprod. 2015 Feb;92(2):56. PubMed PMID: 25537373.

10: Rueda CM, Wells CB, Gisslen T, Jobe AH, Kallapur SG, Chougnet CA. Effect of chorioamnionitis on regulatory T cells in moderate/late preterm neonates. Hum Immunol. 2015 Jan;76(1):65-73. PubMed PMID: 25451985.

 

See all publications on PubMed