George Deepe, MD, Professor

Department of Molecular Genetics
Biochemistry and Microbiology
University of Cincinati

E-Mail: deepegs(at)ucmail.uc.edu
Tel.: 001 513 558 4704

Recent publications:

1: Wüthrich M, Brandhorst TT, Sullivan TD, Filutowicz H, Sterkel A, Stewart D, Li M, Lerksuthirat T, LeBert V, Shen ZT, Ostroff G, Deepe GS Jr, Hung CY, Cole G, Walter JA, Jenkins MK, Klein B. Calnexin Induces Expansion of Antigen-Specific CD4(+) T Cells that Confer Immunity to Fungal Ascomycetes via Conserved Epitopes. Cell Host Microbe. 2015 Apr 8;17(4):452-65. PubMed PMID: 25800545.


2: Verma A, Kroetz DN, Tweedle JL, Deepe GS Jr. Type II cytokines impair host defense against an intracellular fungal pathogen by amplifying macrophage generation of IL-33. Mucosal Immunol. 2015 Mar;8(2):380-9. PubMed PMID: 25118166.

3. Horwath MC, Fecher RA, Deepe GS Jr. Histoplasma capsulatum, lung infection and immunity. Future Microbiol. 2015;10(6):967-75. PubMed PMID: 26059620.

4: Figueroa JA, Vignesh KS, Deepe GS Jr, Caruso J. Selectivity and specificity of small molecule fluorescent dyes/probes used for the detection of Zn2+ and Ca2+ in cells. Metallomics. 2014 Feb;6(2):301-15.PubMed PMID:24356796.


5: Subramanian Vignesh K, Landero Figueroa JA, Porollo A, Caruso JA, Deepe GS Jr. Granulocyte macrophage-colony stimulating factor induced Zn sequestration enhances macrophage superoxide and limits intracellular pathogen survival. Immunity. 2013 Oct 17;39(4):697-710. PubMed PMID: 24138881.

6: Subramanian Vignesh K, Landero Figueroa JA, Porollo A, Caruso JA, Deepe GS Jr. Zinc sequestration: arming phagocyte defense against fungal attack. PLoS Pathog. 2013;9(12):e1003815. Review. PubMed PMID: 24385902.

7: Cole GT, Hung CY, Sanderson SD, Hurtgen BJ, Wüthrich M, Klein BS, Deepe GS, Ostroff GR, Levitz SM. Novel strategies to enhance vaccine immunity against coccidioidomycosis. PLoS Pathog. 2013;9(12):e1003768. PubMed PMID: 24367252.

8: Deepe GS Jr. NADPH oxidase regulates efficacy of vaccination in aspergillosis. J Clin Invest. 2012 May 1;122(5):1608-11. Epub 2012 Apr23. PubMed PMID: 22523062

9: Kroetz DN, Deepe GS. The role of cytokines and chemokines in Histoplasma capsulatum infection. Cytokine. 2012 Apr;58(1):112-7. Review. PubMed PMID: 21871816.http://www.ncbi.nlm.nih.gov/pubmed/20731582

10: Kroetz DN, Deepe GS Jr. CCR5 deficiency mitigates the deleterious effects oftumor necrosis factor a antagonism in murine histoplasmosis. J Infect Dis. 2012Mar 15;205(6):955-63. Epub 2012 Jan 23. PubMed PMID: 22271672

 

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