Kasper Hoebe, PhD, Assistant Professor

Division of Cellular and Molecular Immunology
Cincinnati Children’s Hospital Medical Center

E-Mail: kasper.hoebe@cchmc.org
Tel.: 001 513 803 1056

Recent publications:

1. Lo B, Zhang K, Lu W, Zheng L, Zhang Q, Kanellopoulou C, Zhang Y, Liu Z, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, MoJ, Filipovich AH, Bleesing JJ, Mustillo P, Stephens M, Rueda CM, Chougnet CA,Hoebe K, McElwee J, Hughes JD, Karakoc-Aydiner E, Matthews HF, Price S, Su HC,Rao VK, Lenardo MJ, Jordan MB. AUTOIMMUNE DISEASE. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy. Science. 2015 Jul 24;349(6246):436-40. PubMed PMID:26206937.

2. Lampe K, Endale M, Cashman S, Fang H, Mattner J, Hildeman D, Hoebe K. Slp-76 is a critical determinant of NK-cell mediated recognition of missing-selftargets. Eur J Immunol. 2015 Jul;45(7):2072-83.PubMed PMID: 25929249.

3: Shehata HM, Hoebe K, Chougnet CA. The aged nonhematopoietic environment impairs natural killer cell maturation and function. Aging Cell. 2015 Apr;14(2):191-9. PubMed PMID: 25677698.

4. Endale M, Aksoylar HI, Hoebe K. Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut. Mediators Inflamm.2015;2015:436017. Review. PubMed PMID:25944983.

5. Chen XL, Serrano D, Mayhue M, Hoebe K, Ilangumaran S, Ramanathan S. GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes. PLoS One. 2015 Oct 6;10(10):e0139019. PubMed PMID: 26440416.

6: Boespflug ND, Kumar S, McAlees JW, Phelan JD, Grimes HL, Hoebe K, Hai T, Filippi MD, Karp CL. ATF3 is a novel regulator of mouse neutrophil migration. Blood. 2014 Mar 27;123(13):2084-93. PubMed PMID: 24470589.

7: Tardif V, Manenkova Y, Berger M, Hoebe K, Zuo JP, Yuan C, Kono DH,Theofilopoulos AN, Lawson BR. Critical role of transmethylation in TLR signaling and systemic lupus erythematosus. Clin Immunol. 2013 May;147(2):133-43. PubMed PMID: 23583916.

8: Arnold CN, Barnes MJ, Berger M, Blasius AL, Brandl K, Croker B, Crozat K, DuX, Eidenschenk C, Georgel P, Hoebe K, Huang H, Jiang Z, Krebs P, La Vine D, Li X,Lyon S, Moresco EM, Murray AR, Popkin DL, Rutschmann S, Siggs OM, Smart NG, SunL, Tabeta K, Webster V, Tomisato W, Won S, Xia Y, Xiao N, Beutler B. ENU-induced phenovariance in mice: inferences from 587 mutations. BMC Res Notes. 2012 Oct24;5:577. PubMed PMID: 23095377.

9: Cashman S, Lampe K, Sheridan R, Hoebe K. An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862. PubMed PMID:23162753.

10. Cashman S, Lampe K, Sheridan R, Hoebe K. An ENU mutagenesis approach to dissect "self"-induced immune responses: Unraveling the genetic footprint of immunosurveillance. Oncoimmunology. 2012 Sep 1;1(6):856-862. PubMed PMID:23162753.

See all publications on PubMed